Endocrine Abstracts

IntroductionAmiodarone is a drug commonly used for the treatment of refractory atrial or ventricular arrhythmias. In 20% of patients, amiodarone may cause subclinical or clinically overt hypothyroidism or hyperthyroidism. The high iodine exposure caused by amiodarone treatment interferes with thyroid autoregulation. Two underlying mechanisms are considered to be involved in the pathogenesis of amiodarone-induced thyrotoxicosis (AIT). AIT1 is more common ...